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term
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description
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IBRITUMOMAB TIUXETAN
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A monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment and detection of other types of B-cell tumors. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Ibritumomab binds to the protein called CD20, which is found on B cells. It is linked to the compound tiuxetan. This allows certain radioisotopes to be attached before it is given to a patient. It is a type of monoclonal antibody-chelator conjugate. Also called Zevalin.
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IBUPROFEN
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A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Also called Advil and Motrin.
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ICE REGIMEN
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An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin and Hodgkin lymphomas that have come back and do not respond to other treatments. It includes the drugs ifosfamide, carboplatin, and etoposide phosphate. Also called ICE.
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ICI 182780
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A drug that blocks estrogen activity in the body and is used in the therapy of estrogen-dependent tumors such as breast cancer.
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ICI D1694
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An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA. Also called raltitrexed. It belongs to the family of drugs called thymidylate synthase inhibitors.
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IDARUBICIN
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An anticancer drug that is a type of antitumor antibiotic. Also called 4-demethoxydaunorubicin.
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IDEC-Y2B8 MONOCLONAL ANTIBODY
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An anticancer drug that is a combination of a monoclonal antibody and a radioisotope (yttrium-90). Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. Also called yttrium Y90 ibritumomab tiuxetan.
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IDIOPATHIC
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Describes a disease of unknown cause.
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IDIOPATHIC MYELOFIBROSIS
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A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is marked by an enlarged spleen and progressive anemia. Also called agnogenic myeloid metaplasia, chronic idiopathic myelofibrosis, myelosclerosis with myeloid metaplasia, and primary myelofibrosis.
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IDIOPATHIC PNEUMONIA SYNDROME
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A set of pneumonia-like symptoms (such as fever, chills, coughing, and breathing problems) that occur with no sign of infection in the lung. Idiopathic pneumonia syndrome is a serious condition that can occur after a stem cell transplant.
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